Adam M. Chazin-Gray

This study designs miniprotein inhibitors targeting bacterial adhesins to prevent and treat urinary tract infections.

The paper designs miniprotein inhibitors of the Staphylococcus aureus efflux transporter NorA and identifies a promising inhibitor with a cryo-EM structure showing its binding mechanism.

This paper introduces SNIPR, a synthetic receptor that responds to soluble ligands, enabling targeted CAR T-cell therapy and synthetic cell signaling.

The paper designs EndoTags to trigger endocytosis and degradation of target proteins, enabling tissue-specific targeting and therapeutic applications.