Identifying Novel Candidates for Re-Purposing as Potential Therapeutic Agents for Alzheimer’s disease
Clive G. Ballard, Byron Creese, Ariana P. Gatt, Patrick Doherty, Paul T. Francis, D Whitfield, Anne Corbett, J Corcoran, Diane P. Hanger, Sandrine Thuret, Richard Killick, Gareth Haydn Williams
The paper identifies 19 compounds from the CMAP library that show significant inverse correlation with Alzheimer's disease transcriptome signatures and pass in vitro screening assays.
bioRxiv · Apr 29, 2019 · PreprintNeuroscience