Author

D. Arenz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. S. Dingens· 3 shared J. D. Bloom· 3 shared J. Overbaugh· 3 shared A. Dhar· 2 shared E. Harkins· 2 shared H. Weight· 2 shared K. K. Lee· 2 shared K. Mandaliya· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. S. Dingens

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Functional development of a V3-specific broadly neutralizing antibody isolated from a case of HIV superinfection

M. M. Shipley, V. Mangala Prasad, L. E. Doepker, A. S. Dingens, D. K. Ralph, E. Harkins, A. Dhar, D. Arenz, V. Chohan, H. Weight, K. Mandaliya, J. D. Bloom, F. Matsen, K. K. Lee, J. M. Overbaugh

This study characterizes the development of a V3-specific broadly neutralizing antibody from an HIV superinfection case, revealing unique epitope recognition and escape mechanisms.

bioRxiv · Mar 15, 2021Microbiology

Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies

L. E. Doepker, S. Danon, E. Harkins, D. Ralph, Z. Yaffe, A. Dhar, C. Wagner, M. Stumpf, D. Arenz, J. A. Williams, W. Jaoko, K. Mandaliya, K. K. Lee, F. A. Matsen, J. Overbaugh

This study reconstructs the developmental pathways of HIV-specific ADCC antibodies and identifies mutations required for antigen binding and ADCC function.

bioRxiv · Sep 24, 2020 · PreprintImmunology

Massively parallel profiling of HIV-1 resistance to the fusion inhibitor enfuvirtide

A. S. Dingens, D. Arenz, J. Overbaugh, J. D. Bloom

This study identifies additional resistance mutations to enfuvirtide using deep mutational scanning, expanding the known mechanisms of resistance.

bioRxiv · Nov 19, 2018Microbiology

An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies

A. S. Dingens, D. Arenz, H. Weight, J. Overbaugh, J. D. Bloom

This study maps how single amino-acid mutations in HIV-1 Env affect neutralization by nine broadly neutralizing antibodies, revealing escape mechanisms and informing vaccine and therapy design.

bioRxiv · Aug 31, 2018Immunology