Author

A. R. Subramanya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. L. Marciszyn· 3 shared A. R. Rodan· 2 shared C. R. Boyd-Shiwarski· 2 shared D. J. Shiwarski· 2 shared R. T. Beacham· 2 shared S. E. Griffiths· 2 shared T. R. Kleyman· 2 shared A. Bandaru· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPhysiology

A. L. Marciszyn

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Author profile →

4 papers

Recent·Most cited

Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron

A. Porter, H. E. Vorndran, A. L. Marciszyn, S. M. Mutchler, A. R. Subramanya, T. R. Kleyman, L. M. Hendershot, J. L. Brodsky, T. M. Buck

This study shows that excess dietary sodium partially restores electrolyte imbalance and kidney injury markers in GRP170-deficient mice but not weight or tubule integrity.

bioRxiv · Jan 13, 2024 · PreprintCell Biology

WNK kinases sense molecular crowding and rescue cell volume via phase separation

C. R. Boyd-Shiwarski, D. J. Shiwarski, S. E. Griffiths, R. T. Beacham, L. Norrell, D. E. Morrison, J. Wang, J. R. Mann, W. Tennant, E. N. Anderson, J. Franks, M. Calderon, K. A. Connolly, C. J. Weaver, C. C. Weckerly, , A. R. Subramanya

This study shows WNK1 senses molecular crowding by phase separation to activate volume recovery in hypertonic conditions through phosphorylation-dependent signaling.

bioRxiv · Jan 10, 2022Cell Biology

KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

C. R. Boyd-Shiwarski, R. T. Beacham, J. A. Lashway, K. E. Querry, S. E. Griffiths, D. J. Shiwarski, S. A. Knoell, N. H. Nguyen, L. J. Nkashama, M. N. Valladares, A. Bandaru, A. L. Marciszyn, A. R. Rodan, C.-L. Huang, S. D. Stocker, , A. R. Subramanya

This study shows KS-WNK1 amplifies NCC activity in response to potassium changes via WNK bodies, leading to sex-specific renal salt-wasting and blood pressure sensitivity.

bioRxiv · Mar 12, 2021 · PreprintPhysiology

L-WNK1 is required for BK channel activation in intercalated cells

E. C. Ray, R. Carrisoza, M. Al-Bataineh, A. L. Marciszyn, L. Nkashama, J. C. Chen, A. Winfrey, D. Flores, P. Wu, W. C. Wang, c.-l. wang, A. R. Subramanya, T. R. Kleyman, L. M. Satlin

This study shows that L-WNK1 in intercalated cells enhances BK channel activity in response to a high K+ diet, which is critical for urinary K+ secretion.

bioRxiv · Jan 26, 2021Physiology