Author

D. G. Fernig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. Su· 2 shared B. Ebrahimi· 1 shared C. J. Mycroft-West· 1 shared C. Stylianou· 1 shared C. Sun· 1 shared D. J. Rigden· 1 shared D. M. Simpson· 1 shared E. A. Yates· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

D. Su

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Author profile →

5 papers

Recent·Most cited

Macromolecular crowding by hyaluronan: implications for binding reactions in the pericellular matrix and at the cell surface

D. G. Fernig

This study examines how hyaluronan affects FGF-2 binding to heparin in crowded environments, showing that higher concentrations of hyaluronan significantly reduce binding rates.

bioRxiv · Jan 3, 2024 · PreprintBiochemistry

Raman mapping glucose metabolites during human mesenchymal stem cell adipogenesis

J. D. Hobley, G. S. Subramanian, V. Nurcombe, S. Gorelik, P. In Yee, C. Stylianou, S. Cool, D. G. Fernig, M. J. Lear

This study uses Raman mapping to track lipid metabolite changes in human mesenchymal stem cells during adipogenesis, revealing temporal shifts in lipid composition.

bioRxiv · Apr 19, 2020 · PreprintCell Biology

The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding.

C. J. Mycroft-West, D. Su, S. Elli, Y. Li, S. E. Guimond, G. J. Miller, J. E. Turnbull, E. A. Yates, M. Guerrini, D. G. Fernig, M. Andrade de Lima, M. A. Skidmore

The paper shows that SARS-CoV-2 Spike S1 RBD undergoes a conformational change when bound to heparin, suggesting potential for heparin as a therapeutic.

bioRxiv · Feb 29, 2020 · PreprintBiochemistry

The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis

Q. M. Nunes, D. Su, P. J. Brownridge, D. M. Simpson, C. Sun, y. li, P. T. P. Bui, X. Zhang, W. Huang, D. J. Rigden, R. J. Beynon, R. Sutton, D. G. Fernig

This study identifies extracellular heparin-binding proteins (HBPs) in normal and acute pancreatitis mouse pancreas and plasma, revealing their roles in homeostasis and inflammation.

PLOS ONE · Jun 18, 2019Peer-reviewedBiochemistry

Enhanced inhibition of influenza virus infection by peptide-noble metal nanoparticle conjugates

Z. Alghrair, D. G. Fernig, B. Ebrahimi

This study shows that conjugating the antiviral peptide FluPep to gold and silver nanoparticles enhances its antiviral potency against influenza virus.

bioRxiv · May 17, 2018Biochemistry