Author

D. J. Hart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Salahudeen· 2 shared A. Batish· 2 shared C. J. Kuo· 2 shared S. M. De la O· 2 shared T. Usui· 2 shared A. C. Zarco· 1 shared A. J. M. Santos· 1 shared A. R. Smith· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. A. Salahudeen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pan-cancer organoid validation of tumor outlier chromosomal amplification events

A. A. Salahudeen, K. Yuki, J. Seoane, A. T. Mah, A. R. Smith, K. Kolahi, S. M. De la O, D. J. Hart, J. Ding, Z. Ma, S. A. Barkal, N. D. Shukla, H. C. Zhang, M. A. Cantrell, A. Batish, , C. J. Kuo

The paper validates oncogenic chromosomal amplification events across multiple cancers using organoid models and functional assays.

bioRxiv · Oct 5, 2021 · PreprintCancer Biology

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

A. A. Salahudeen, S. S. Choi, A. Rustagi, J. Zhu, S. M. de la O, R. A. Flynn, M. Margalef-Catala, A. J. M. Santos, J. Ju, A. Batish, V. van Unen, T. Usui, G. X. Y. Zheng, C. E. Edwards, L. E. Wagar, , C. J. Kuo

This paper develops a feeder-free organoid culture system for human distal lung progenitors and demonstrates SARS-CoV-2 infection of club cells in a novel in vitro model.

bioRxiv · Jul 27, 2020 · PreprintCell Biology

Molecular Basis of Host-Adaptation Interactions between Influenza Virus Polymerase PB2 Subunit and ANP32A

A. C. Zarco, S. Kalayil, D. Maurin, N. Salvi, E. Delaforge, S. Milles, M. R. Jensen, D. J. Hart, S. Cusack, M. Blackledge

This study identifies molecular interactions between influenza PB2 subunit variants and ANP32A that explain host adaptation and species-specific restriction of viral replication.

bioRxiv · Mar 18, 2020Biophysics