Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures
A. A. Salahudeen, S. S. Choi, A. Rustagi, J. Zhu, S. M. de la O, R. A. Flynn, M. Margalef-Catala, A. J. M. Santos, J. Ju, A. Batish, V. van Unen, T. Usui, G. X. Y. Zheng, C. E. Edwards, L. E. Wagar, , C. J. Kuo
This paper develops a feeder-free organoid culture system for human distal lung progenitors and demonstrates SARS-CoV-2 infection of club cells in a novel in vitro model.
bioRxiv · Jul 27, 2020 · PreprintCell Biology