Author

K. Yuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Ding· 2 shared A. A. Salahudeen· 1 shared A. Batish· 1 shared A. Califano· 1 shared A. McCormick· 1 shared A. R. Smith· 1 shared A. Sura· 1 shared A. T. Mah· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

J. Ding

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The landscape of immune dysregulation in pediatric sepsis at a single-cell resolution

F. Alhamdan, S. Koutsogiannaki, K. Yuki

This study analyzes single-cell transcriptomic data from pediatric sepsis patients to identify immune dysregulation patterns and compare them to adult sepsis.

bioRxiv · Jan 17, 2024Immunology

Neutrophil extracellular traps formation is associated with postoperative complications in neonates and infants undergoing congenital cardiac surgery

W. Maisat, L. Hou, S. Sandhu, Y.-C. Sin, S. Kim, H. Van Pelt, Y. Chen, S. Emani, S. w. Kong, S. Emani, J. Ibla, K. Yuki

This study finds that neutrophil extracellular traps (NETs) formation is linked to postoperative complications in neonates and infants after congenital cardiac surgery.

bioRxiv · Dec 21, 2023 · PreprintImmunology

Therapeutic modulation of the blood-brain barrier and ischemic stroke by a bioengineered FZD4-selective WNT surrogate

J. Ding, S.-J. Lee, L. Vlahos, K. Yuki, C. Rada, V. van Unen, M. Vuppalapaty, H. Chen, A. Sura, A. McCormick, M. Tomaske, S. Alwahabi, H. Nguyen, W. Nowatzke, L. Kim, , C. Kuo

This study develops a bioengineered FZD4-selective WNT surrogate that improves BBB function and reduces ischemic stroke damage in mice.

bioRxiv · Oct 13, 2022 · PreprintPhysiology

Pan-cancer organoid validation of tumor outlier chromosomal amplification events

A. A. Salahudeen, K. Yuki, J. Seoane, A. T. Mah, A. R. Smith, K. Kolahi, S. M. De la O, D. J. Hart, J. Ding, Z. Ma, S. A. Barkal, N. D. Shukla, H. C. Zhang, M. A. Cantrell, A. Batish, , C. J. Kuo

The paper validates oncogenic chromosomal amplification events across multiple cancers using organoid models and functional assays.

bioRxiv · Oct 5, 2021 · PreprintCancer Biology

Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA.

F. Hamano, K. Matoba, T. Hashidate, T. Suzuki, K. Miura, D. Hishikawa, T. Harayama, K. Yuki, Y. Kita, N. N. Noda, T. Shimizu, H. Shindou

The paper identifies key residues and an acyl-CoA-binding pocket in mouse LPCAT2 using homology modeling, providing structural insights for drug development against PAF-related diseases.

bioRxiv · Oct 31, 2020Biochemistry