Ciliary protein CEP290 regulates focal adhesion via microtubule system in non-ciliated cells
K. Matsuo, Y. Nakajima, M. Shigeta, D. Kobayashi, S. Sakaki, S. Inoue, N. Takeshita, A. Ueyama, K. Nishikawa, R. Saba, T. Yokoyama, K. Yashiro
This study identifies a cilia-independent role of CEP290 in non-ciliated cells by regulating microtubule elongation and focal adhesion through its interaction with APC.
bioRxiv · Apr 2, 2023 · PreprintCell Biology