Author

D. Kurian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:virus· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

P. Digard· 3 shared A. C. Gill· 1 shared A. Miguelez-Crespo· 1 shared B. R. Walker· 1 shared B. Tesla· 1 shared C. F. Pereira· 1 shared C. P. Sharp· 1 shared C. Tait-Burkard· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

P. Digard

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ATP-Binding Cassette Family C member 1 constrains metabolic responses to high-fat diet in male mice

E. Villalobos, A. Miguelez-Crespo, R. A. Morgan, L. Ivatt, D. Kurian, J. Aguilar, R. A. Kline, T. M. Wishart, N. Morton, R. H. Stimson, R. Andrew, B. R. Walker, M. Nixon

This study shows that ABCC1 deficiency in male mice affects glucose metabolism and insulin tolerance on a high-fat diet without altering tissue corticosterone levels.

bioRxiv · Jan 23, 2024 · PreprintPhysiology

Understanding off-target growth defects introduced to influenza A virus by synonymous recoding

C. P. Sharp, E. H. Thompson, B. Tesla, D. Kurian, P. Simmonds, P. Digard, E. R. Gaunt

This study identifies compensatory mutations that cause replication defects in a CpG-enriched influenza A virus, revealing polymerase slippage and type I interferon induction as key mechanisms.

bioRxiv · Jul 17, 2023 · PreprintMicrobiology

Secreted SARS-CoV-2 ORF8 modulates the cytokine expression profile of human macrophages

N. Kriplani, S. M. R. Clohisey, S. Fonseca, S. Fletcher, H.-M. Lee, J. Ashworth, D. Kurian, S. J. Lycett, C. Tait-Burkard, J. K. Baillie, M. E. J. Woolhouse, S. R. Carding, J. P. Stewart, P. Digard

This study shows that SARS-CoV-2 ORF8 protein modulates cytokine expression in human macrophages, with sequence polymorphisms affecting IL-6 and IL-8 secretion.

bioRxiv · Aug 13, 2021 · PreprintMicrobiology

Pleotropic effects of mutations in the effector domain of influenza A virus NS1 protein

C. F. Pereira, H. M. Wise, D. Kurian, R. M. Pinto, M. J. Amorim, A. C. Gill, P. Digard

The paper investigates how mutations in the NS1 protein of influenza A virus affect its ability to promote viral mRNA nuclear export and interacts with cellular factors.

bioRxiv · Aug 13, 2018Microbiology