Author

C. Tait-Burkard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. L. Fletcher· 3 shared A. Daniels· 2 shared M. O'Shea· 2 shared N. Craig· 2 shared N. Kriplani· 2 shared P. Digard· 2 shared S. Fletcher· 2 shared A. B. Lawrence· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

S. L. Fletcher

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Emergence and spread of feline infectious peritonitis due to a highly pathogenic canine/feline recombinant coronavirus

C. Atippa, A. S. Warr, D. Epaminondas, M. O'Shea, A. J. Hanton, S. L. Fletcher, A. Malbon, M. Lyraki, R. Hammond, A. Hardas, A. Zanti, S. Loukaidou, M. Gentil, D. Gunn-Moore, S. Mazeri, C. Tait-Burkard

This study reports the emergence of a highly pathogenic FCoV-CCoV recombinant causing a rapidly spreading FIP outbreak in Cyprus, with evidence of direct transmission and potential receptor binding changes.

bioRxiv · Nov 8, 2023 · PreprintMicrobiology

One for all - Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses

A. Daniels, S. L. Fletcher, H. E. M. Kerr, A. Kratzel, N. Kriplani, N. Craig, C. J. Hastie, P. Davies, P. Digard, V. Thiel, C. Tait-Burkard

This paper identifies Caki-1 human kidney cells as a highly susceptible model for studying multiple respiratory viruses, including coronaviruses and influenza, offering a versatile platform for cross-virus comparison.

bioRxiv · Oct 25, 2022 · PreprintMicrobiology

Direct lysis RT-qPCR of SARS-CoV-2 in cell culture supernatant allows for fast and accurate quantification of virus, opening a vast array of applications

N. Craig, S. L. Fletcher, A. Daniels, C. Newman, M. O'Shea, A. Warr, C. Tait-Burkard

This paper introduces a direct lysis RT-qPCR method for fast, accurate, and cost-effective quantification of SARS-CoV-2 in cell culture supernatant, enabling high-throughput applications.

bioRxiv · Nov 30, 2021 · PreprintMicrobiology

Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock

S. Meek, T. Watson, L. Eory, G. McFarlane, F. J. Wynne, S. McCleary, L. E. M. Dunn, E. M. Charlton, C. Craig, B. Shih, T. Regan, R. M. Taylor, L. Sutherland, A. Gossner, C. Chintoan-Uta, , T. Burdon

The paper uses stem cell-derived macrophages from livestock to study host-pathogen interactions, showing they can be infected by important viruses and genetically modified.

bioRxiv · Sep 10, 2021Immunology

Secreted SARS-CoV-2 ORF8 modulates the cytokine expression profile of human macrophages

N. Kriplani, S. M. R. Clohisey, S. Fonseca, S. Fletcher, H.-M. Lee, J. Ashworth, D. Kurian, S. J. Lycett, C. Tait-Burkard, J. K. Baillie, M. E. J. Woolhouse, S. R. Carding, J. P. Stewart, P. Digard

This study shows that SARS-CoV-2 ORF8 protein modulates cytokine expression in human macrophages, with sequence polymorphisms affecting IL-6 and IL-8 secretion.

bioRxiv · Aug 13, 2021 · PreprintMicrobiology