Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
L. Lu, F. Zhang, B. Oude Munnink, E. Munger, R. Sikkema, S. Pappa, K. Tsioka, A. Sinigaglia, E. D. Molin, B. Shih, A. Gunther, A. Pohlmann, M. Beer, R. A. Taylor, F. A. Bartumeus, , M. Koopmans
This study analyzes the phylogeographic patterns of West Nile Virus in Europe, identifying key drivers like agriculture and lineage diversity.
bioRxiv · Nov 10, 2022Evolutionary Biology
This study analyzes the evolution of SARS-CoV-2 spike protein over time, showing increased antibody evasion and stronger RBD-ACE2 binding.
bioRxiv · Oct 15, 2022 · PreprintMicrobiology
N. Kriplani, S. M. R. Clohisey, S. Fonseca, S. Fletcher, H.-M. Lee, J. Ashworth, D. Kurian, S. J. Lycett, C. Tait-Burkard, J. K. Baillie, M. E. J. Woolhouse, S. R. Carding, J. P. Stewart, P. Digard
This study shows that SARS-CoV-2 ORF8 protein modulates cytokine expression in human macrophages, with sequence polymorphisms affecting IL-6 and IL-8 secretion.
bioRxiv · Aug 13, 2021 · PreprintMicrobiology
J. Flannery, B. Shih, I. R. Haga, M. Ashby, A. Corla, S. King, G. L. Freimanis, N. Polo, A. Tse, C. Brackman, J. Chan, P. Pun, A. D. Ferguson, A. Law, S. J. Lycett, , P. Beard
This paper reports the first detection of lumpy skin disease virus in Hong Kong, identifying a novel strain genetically distinct from previous outbreaks.
bioRxiv · Apr 20, 2021Microbiology
G. Rossi, J. Crispell, T. Brough, S. J. Lycett, P. C. L. White, A. Allen, R. J. Ellis, S. V. Gordon, R. Harwood, E. Palkopoulou, E. Presho, R. Skuce, G. C. Smith, R. R. Kao
The paper analyzes an M. bovis outbreak in cattle and badgers using mathematical modeling, machine learning, and Bayesian methods, finding a single introduction from Northern Ireland and two-phase transmission dynamics.
bioRxiv · Nov 12, 2020Ecology
G. Rossi, J. Crispell, D. Balaz, S. J. Lycett, R. J. Delahay, R. R. Kao
The paper develops an analytical method to infer transmission probabilities between hosts using low-diversity pathogen sequence data and sampling times, applied to M. bovis in cattle and badgers.
bioRxiv · Jun 11, 2020Ecology
A. L. Clements, J. E. Sealy, T. P. Peacock, J.-R. Sadeyen, S. Hussain, S. J. Lycett, H. Shelton, P. Digard, M. Iqbal
This paper identifies a single amino acid change in the PA protein of H9N2 avian influenza viruses that enhances virulence and replication in poultry.
bioRxiv · May 27, 2020Microbiology
J. H. Forth, L. F. Forth, S. J. Lycett, L. Bell-Sakyi, G. M. Keil, S. Blome, S. Calvignac-Spencer, A. Wissgott, J. Krause, D. Hoeper, H. Kampen, M. Beer
The paper identifies ASFV-like integrated elements in soft tick genomes, suggesting an ancient co-evolutionary arms race between ticks and ASFV.
bioRxiv · Mar 8, 2020 · PreprintMicrobiology
L. Lu, L. Brierley, G. Robertson, F. Zhang, S. J. Lycett, D. Smith, M. Chase-Topping, P. Simmonds, M. E. J. Woolhouse
The paper investigates the evolutionary origins of epidemic potential in human RNA viruses, finding that most transmissible lineages evolved from non-human viruses.
bioRxiv · Sep 18, 2019 · PreprintEvolutionary Biology
H. M. Wise, E. Gaunt, J. Ping, B. Holzer, S. Jasim, S. J. Lycett, L. Murphy, A. Livesey, R. Brown, N. Smith, S. Morgan, B. Clark, K. Kudryavtseva, P. M. Beard, J. Nguyen-Van-Tam, , P. Digard
The paper identifies an alternative AUG codon in the 2009 pandemic influenza A virus as a virulence factor contributing to pathogenicity in swine and humans.
bioRxiv · Sep 4, 2019 · PreprintMicrobiology