Author

D. Kwiatkowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Evolutionary Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Beck-Sickinger· 1 shared A. Elhassan· 1 shared A. Hussain· 1 shared A. Koch· 1 shared A. Miles· 1 shared A. Moran-Horowich· 1 shared A. O. O'Reilly· 1 shared A. Saeed· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

A. Beck-Sickinger

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Author profile →

5 papers

Recent·Most cited

The rural urban divide, insights from immuno-genetic profiles and implications for health

R. Hamad, N. A. Eid, A. Saeed, S. A. E. Abuswar, A. Hussain, K. Rockett, D. Kwiatkowski, M. Ibrahim, I. Elhassan, A. Elhassan

The paper analyzes genotype and gene expression differences between rural and urban populations in eastern Sudan, finding higher cytokine expression and genetic variation in rural samples linked to health disparities.

bioRxiv · Sep 8, 2023Immunology

A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In Vivo

J. Hernandez, X. Wang, M. Vazquez-Segoviano, M. F. Sobral-Reyes, A. Moran-Horowich, M. Sundberg, M. Lopez-Marfil, D. O. Lopez-Cantu, C. Probst, G. Ruiz-Esparza, K. Giannikou, E. Henske, D. Kwiatkowski, M. Sahin, D. R. Lemos

This paper develops a tissue-bioengineering strategy using TSC patient-derived kidney organoids to model rare kidney diseases in vivo and test therapeutic approaches.

bioRxiv · Oct 20, 2021Bioengineering

Structures of active melanocortin-4 receptor--Gs-protein complexes with NDP-α-MSH and setmelanotide

N. A. Heyder, G. Kleinau, D. Speck, A. Schmidt, S. Paisdzior, M. Szczepek, B. Bauer, A. Koch, M. Gallandi, D. Kwiatkowski, J. Bürger, T. Mielke, A. Beck-Sickinger, P. W. Hildebrand, C. M. T. Spahn, , P. Scheerer

The paper presents cryo-EM structures of MC4R-Gs complexes with NDP-α-MSH and setmelanotide, revealing ligand-specific interactions and activation mechanisms.

bioRxiv · Apr 22, 2021Biochemistry

Evolution of the insecticide target Rdl in African Anopheles is driven by interspecific andinterkaryotypic introgression

X. Grau-Bove, S. Tomlinson, A. O. O'Reilly, N. J. Harding, A. Miles, D. Kwiatkowski, M. J. Donnelly, D. Weetman, The Anopheles gambiae 1000 Genomes Consortium

The paper examines the evolution of insecticide resistance in Anopheles mosquitoes, showing how Rdl mutations spread through selective sweeps and introgression across species and karyotypes.

bioRxiv · Dec 17, 2019Evolutionary Biology

Precision identification and prediction of high mortality phenotypes and disease progression pathways in severe malaria without requiring longitudinal data

T. Hoffmann, I. G. Johnston, S. Greenbury, O. Cominetti, M. Jallow, D. Kwiatkowski, M. Barahona, N. S. Jones, C. Casals-Pascual

bioRxiv · Sep 24, 2018Pathology