Author

N. J. Harding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:whole-genome sequencing· 2 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Miles· 2 shared D. Weetman· 2 shared M. J. Donnelly· 2 shared The Anopheles gambiae 1000 Genomes Consortium· 2 shared A. O. O'Reilly· 1 shared C. S. Clarkson· 1 shared D. Kwiatkowski· 1 shared D. P. Kwiatkowski· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersEvolutionary Biology

A. Miles

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2 papers

Recent·Most cited

Evolution of the insecticide target Rdl in African Anopheles is driven by interspecific andinterkaryotypic introgression

X. Grau-Bove, S. Tomlinson, A. O. O'Reilly, N. J. Harding, A. Miles, D. Kwiatkowski, M. J. Donnelly, D. Weetman, The Anopheles gambiae 1000 Genomes Consortium

The paper examines the evolution of insecticide resistance in Anopheles mosquitoes, showing how Rdl mutations spread through selective sweeps and introgression across species and karyotypes.

bioRxiv · Dec 17, 2019Evolutionary Biology

Whole genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes

E. R. Lucas, A. Miles, N. J. Harding, C. S. Clarkson, M. K. N. Lawniczak, D. P. Kwiatkowski, D. Weetman, M. J. Donnelly, The Anopheles gambiae 1000 Genomes Consortium

The paper uses whole-genome sequencing to identify copy number variations (CNVs) in Anopheles gambiae linked to insecticide resistance, finding CNVs enriched for resistance-related genes and under positive selection.

bioRxiv · Aug 25, 2018Evolutionary Biology