D. L. Goldblatt

Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming

The paper shows that CpG ODNs interact with mitochondrial VDAC1 to induce antimicrobial ROS in lung epithelial cells, offering a new therapeutic strategy for pneumonia without antibiotics.

Epithelial Immunomodulation by Aerosolized Toll-like Receptor Agonists Attenuates Allergic Responsiveness in Mice

Aerosolized Toll-like receptor agonists reduce allergic inflammation in mice by modulating airway epithelial cell responses to allergens.

Immune modulation to improve survival of respiratory virus infections in mice

The paper shows that Pam2-ODN treatment improves survival in mice infected with a paramyxovirus by reducing viral burden and blocking CD8+ T cell-driven inflammation.

Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8+ T cell-mediated immunopathology

This study shows that Pam2-ODN treatment improves survival in mice with Sendai virus pneumonia by inactivating the virus and reducing CD8+ T cell-mediated inflammation.

Aerosolized TLR Agonists Suppress Acute Sendai Virus Lung Infection and Chronic Airway Disease in Mice

The paper shows that aerosolized TLR agonists reduce Sendai virus lung burden and chronic asthma-like disease in mice by suppressing inflammation and IL-33 production.