A. M. Jaramillo

The Colon Mucosal Sialylglycome Is Redox-Regulated by the Golgi Enzyme QSOX1

This study shows that QSOX1 regulates sialylation of the colon glycome by forming disulfides in Golgi glycosyltransferases, not by catalyzing mucin crosslinking.

Epithelial Immunomodulation by Aerosolized Toll-like Receptor Agonists Attenuates Allergic Responsiveness in Mice

Aerosolized Toll-like receptor agonists reduce allergic inflammation in mice by modulating airway epithelial cell responses to allergens.

Immune modulation to improve survival of respiratory virus infections in mice

The paper shows that Pam2-ODN treatment improves survival in mice infected with a paramyxovirus by reducing viral burden and blocking CD8+ T cell-driven inflammation.

Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8+ T cell-mediated immunopathology

This study shows that Pam2-ODN treatment improves survival in mice with Sendai virus pneumonia by inactivating the virus and reducing CD8+ T cell-mediated inflammation.

Aerosolized TLR Agonists Suppress Acute Sendai Virus Lung Infection and Chronic Airway Disease in Mice

The paper shows that aerosolized TLR agonists reduce Sendai virus lung burden and chronic asthma-like disease in mice by suppressing inflammation and IL-33 production.

Different Munc18 Proteins Mediate Baseline and Stimulated Airway Mucin Secretion

The paper identifies distinct roles of Munc18 isoforms in baseline and stimulated airway mucin secretion, showing Munc18b's protective role in asthma and cystic fibrosis models.