Author

J. Pantaleon Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. E. Evans· 4 shared D. L. Goldblatt· 3 shared M. J. Tuvim· 3 shared S. Wali· 3 shared A. M. Jaramillo· 2 shared B. F. Dickey· 2 shared J. R. Flores· 2 shared Y. Wang· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersImmunology

S. E. Evans

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4 papers

Recent·Most cited

Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming

Y. Wang, V. V. Kulkarni, J. Pantaleon Garcia, M. M. Leiva-Juarez, D. L. Goldblatt, F. Gulraiz, J. Chen, S. R. Donepudi, P. L. Lorenzi, H. Wang, L.-J. Wong, M. J. Tuvim, S. E. Evans

The paper shows that CpG ODNs interact with mitochondrial VDAC1 to induce antimicrobial ROS in lung epithelial cells, offering a new therapeutic strategy for pneumonia without antibiotics.

bioRxiv · Jan 19, 2023 · PreprintImmunology

Immune modulation to improve survival of respiratory virus infections in mice

S. Wali, J. R. Flores, A. M. Jaramillo, D. L. Goldblatt, J. Pantaleon Garcia, M. J. Tuvim, B. F. Dickey, S. E. Evans

The paper shows that Pam2-ODN treatment improves survival in mice infected with a paramyxovirus by reducing viral burden and blocking CD8+ T cell-driven inflammation.

bioRxiv · Apr 16, 2020 · PreprintImmunology

Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8+ T cell-mediated immunopathology

S. Wali, J. R. Flores, A. M. Jaramillo, D. L. Goldblatt, J. Pantaleon Garcia, M. J. Tuvim, B. F. Dickey, S. E. Evans

This study shows that Pam2-ODN treatment improves survival in mice with Sendai virus pneumonia by inactivating the virus and reducing CD8+ T cell-mediated inflammation.

bioRxiv · Jan 30, 2020 · PreprintImmunology

Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation to Protect against Bacterial Infections

H. Ware, V. Kulkarni, Y. Wang, M. Leiva, C. Kirkpatrick, J. Pantaleon Garcia, S. Wali, W. Sikkema, J. Tour, S. E. Evans

This study shows that inhaled Pam2-ODN induces lung epithelial ROS production from multiple sources, enhancing antibacterial resistance against Pseudomonas aeruginosa.

bioRxiv · Nov 15, 2018Immunology