Author

J. R. Flores

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. M. Jaramillo· 3 shared B. F. Dickey· 3 shared D. L. Goldblatt· 3 shared S. E. Evans· 3 shared S. Wali· 3 shared J. Pantaleon Garcia· 2 shared M. J. Tuvim· 2 shared A. C. Bippus· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

A. M. Jaramillo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Living apart if you can - how genetically and developmentally controlled sex has shaped the evolution of liverworts

X. He, J. R. Flores, Y. Sun, J. L. Bowman

This study investigates the evolutionary mechanisms of sexual systems in liverworts, showing dioicy is ancestral and more stable than monoicy, driven by genetic and environmental factors.

bioRxiv · Feb 8, 2021 · PreprintEvolutionary Biology

Immune modulation to improve survival of respiratory virus infections in mice

S. Wali, J. R. Flores, A. M. Jaramillo, D. L. Goldblatt, J. Pantaleon Garcia, M. J. Tuvim, B. F. Dickey, S. E. Evans

The paper shows that Pam2-ODN treatment improves survival in mice infected with a paramyxovirus by reducing viral burden and blocking CD8+ T cell-driven inflammation.

bioRxiv · Apr 16, 2020 · PreprintImmunology

Rooting morphologically divergent taxa - slow-evolving sequence data might help

J. R. Flores, A. C. Bippus, A. M. Tomescu, N. E. Bell, J. T. Hyvonen

This study uses sequence data from conservative genes to improve the phylogeny of morphologically divergent mosses, finding that large gametophyte size evolved independently in multiple lineages.

bioRxiv · Mar 15, 2020 · PreprintEvolutionary Biology

Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8+ T cell-mediated immunopathology

S. Wali, J. R. Flores, A. M. Jaramillo, D. L. Goldblatt, J. Pantaleon Garcia, M. J. Tuvim, B. F. Dickey, S. E. Evans

This study shows that Pam2-ODN treatment improves survival in mice with Sendai virus pneumonia by inactivating the virus and reducing CD8+ T cell-mediated inflammation.

bioRxiv · Jan 30, 2020 · PreprintImmunology

Aerosolized TLR Agonists Suppress Acute Sendai Virus Lung Infection and Chronic Airway Disease in Mice

D. L. Goldblatt, J. R. Flores, G. Valverde Ha, A. M. Jaramillo, S. Tkachman, C. K. Kirkpatrick, S. Wali, B. Hernandez, D. Ost, B. Scott, J. Chen, S. E. Evans, M. Tuvim, B. F. Dickey

The paper shows that aerosolized TLR agonists reduce Sendai virus lung burden and chronic asthma-like disease in mice by suppressing inflammation and IL-33 production.

bioRxiv · Jun 13, 2019 · PreprintImmunology