Ketogenic Diet Prevents Heart Failure from Defective Mitochondrial Pyruvate Metabolism
K. S. McCommis, A. Kovacs, C. J. Weinheimer, T. M. Shew, T. R. Koves, O. R. Ilkayeva, D. R. Kamm, K. D. Pyles, M. T. King, R. L. Veech, B. J. DeBosch, D. M. Muoio, R. W. Gross, B. N. Finck
This study shows that a ketogenic diet prevents heart failure in mice with defective mitochondrial pyruvate metabolism by reversing cardiac remodeling and dysfunction.
bioRxiv · Feb 21, 2020Physiology