Author

T. M. Shew

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. J. Lutkewitte· 3 shared B. N. Finck· 3 shared A. LaPoint· 2 shared D. Ferguson· 2 shared J. M. Singer· 2 shared M. He· 2 shared A. Kovacs· 1 shared A. M. Hall· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPhysiology

A. J. Lutkewitte

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mitochondrial Pyruvate Carrier Inhibition Attenuates Hepatic Stellate Cell Activation and Liver Injury in a Mouse Model of Metabolic Dysfunction-associated Steatotic Liver Disease

M. Habibi, D. Ferguson, S. J. Eichler, M. M. Chan, A. LaPoint, T. M. Shew, M. He, A. J. Lutkewitte, J. D. Schilling, K. Y. Cho, G. Patti, B. N. Finck

bioRxiv · Feb 13, 2023 · PreprintPhysiology

Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.

A. LaPoint, J. M. Singer, D. Ferguson, T. M. Shew, K. RenKemeyer, H. Palacios, R. Field, M. Shankaran, G. I. Smith, J. Yoshino, M. He, G. J. Patti, M. Hellerstein, S. Klein, J. R. Brestoff, , A. J. Lutkewitte

The paper shows that lower adipose lipin 1 in humans correlates with metabolic issues, and mice lacking adipocyte lipin 1 develop metabolic disorders.

bioRxiv · Feb 1, 2023 · PreprintPhysiology

Monoacylglycerol disrupts Golgi structure and perilipin 2 association with lipid droplets

L.-A. L. S. Harris, J. R. Skinner, T. M. Shew, N. A. Abumrad, N. Wolins

This study shows that monoacylglycerols disrupt Golgi structure and perilipin 2 association with lipid droplets in enterocytes and fibroblasts.

bioRxiv · Jul 9, 2021 · PreprintCell Biology

Antisense oligonucleotides against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

A. J. Lutkewitte, J. M. Singer, T. M. Shew, M. R. Martino, A. M. Hall, B. N. Finck

This study shows that Mogat1 ASOs improve glucose metabolism in mice independently of Mogat1 knockdown or IFNAR-1 activation.

bioRxiv · Aug 5, 2020Physiology

Ketogenic Diet Prevents Heart Failure from Defective Mitochondrial Pyruvate Metabolism

K. S. McCommis, A. Kovacs, C. J. Weinheimer, T. M. Shew, T. R. Koves, O. R. Ilkayeva, D. R. Kamm, K. D. Pyles, M. T. King, R. L. Veech, B. J. DeBosch, D. M. Muoio, R. W. Gross, B. N. Finck

This study shows that a ketogenic diet prevents heart failure in mice with defective mitochondrial pyruvate metabolism by reversing cardiac remodeling and dysfunction.

bioRxiv · Feb 21, 2020Physiology