Author

R. W. Gross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Kovacs· 1 shared B. J. DeBosch· 1 shared B. N. Finck· 1 shared C. J. Weinheimer· 1 shared C. M. Jenkins· 1 shared D. M. Muoio· 1 shared D. R. Kamm· 1 shared I. Miller· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

A. Kovacs

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Ketogenic Diet Prevents Heart Failure from Defective Mitochondrial Pyruvate Metabolism

K. S. McCommis, A. Kovacs, C. J. Weinheimer, T. M. Shew, T. R. Koves, O. R. Ilkayeva, D. R. Kamm, K. D. Pyles, M. T. King, R. L. Veech, B. J. DeBosch, D. M. Muoio, R. W. Gross, B. N. Finck

This study shows that a ketogenic diet prevents heart failure in mice with defective mitochondrial pyruvate metabolism by reversing cardiac remodeling and dysfunction.

bioRxiv · Feb 21, 2020Physiology

A novel dimeric active site and regulation mechanism revealed by the crystal structure of iPLA2β

K. R. Malley, O. Koroleva, I. Miller, R. Sanishvili, C. M. Jenkins, R. W. Gross, S. Korolev

The paper presents the first crystal structure of iPLA2β, revealing a dimeric active site and regulation mechanism that could inform therapeutic inhibitor development.

bioRxiv · Sep 29, 2017Biochemistry