Author

D. M. Osbourn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Mushtaq· 1 shared A. R. Odom John· 1 shared A. Sateriale· 1 shared C. D. Huston· 1 shared C. L. M. J. Verlinde· 1 shared C. S. Dowd· 1 shared C.-A. D. Burnham· 1 shared D. W. Griggs· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Mushtaq

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Spontaneous selection of Cryptosporidium drug resistance in a calf model of infection

M. M. Hasan, E. E. Stebbins, R. K. M. Choy, J. R. Gillespie, E. de Hostos, P. J. Miller, A. Mushtaq, R. M. Ranade, J. E. Teixeira, C. L. M. J. Verlinde, A. Sateriale, Z. Zhang, D. M. Osbourn, D. W. Griggs, E. Fan, , C. D. Huston

This study reports the spontaneous emergence of drug resistance in Cryptosporidium parvum infected calves treated with a methionyl-tRNA synthetase inhibitor, highlighting the potential for anticryptosporidial resistance.

bioRxiv · Jan 4, 2021Microbiology

Antimicrobial prodrug activation by the staphylococcal glyoxalase GloB

M. O. Mikati, J. J. Miller, D. M. Osbourn, N. Ghebremichael, I. T. Shah, C.-A. D. Burnham, K. M. Heidel, V. C. Yan, F. L. Mueller, C. S. Dowd, R. L. Edwards, A. R. Odom John

This study identifies GloB as a bacterial enzyme that activates carboxy ester prodrugs, suggesting its potential for developing targeted prodrug therapies against staphylococcal species.

ACS Infectious Diseases · Oct 29, 2020Peer-reviewedMicrobiology