ImmunologybioRxiv
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens
A. A. de Waard, T. Verkerk, K. Hoefakker…·R. M. Spaapen
The paper identifies TAP-independent antigen presentation in healthy cells using a T cell clone and highlights the need for comprehensive testing of healthy cell types to safely target antigens for immunotherapy.
DOI 10.1016/j.isci.2021.102051