D. Pereira

Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis

This study uses biophysical methods to analyze AP2 interactions with biomimetic membranes, revealing insights into clathrin-mediated endocytosis mechanisms.

Large-scale analyses reveal the contribution of adaptive evolution in pathogenic and non-pathogenic fungal species

This study analyzes 2,478 fungal genomes to compare adaptive evolution rates across 20 species, finding that high adaptation rates are not exclusive to pathogens.

Polybacterial intracellular coinfection of epithelial stem cells in periodontitis

This study identifies polybacterial intracellular co-infection in human periodontal epithelial cells, revealing its proinflammatory effects and potential role in chronic diseases.

SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy

SCD inhibition induces AML cell death and synergizes with chemotherapy to prolong survival in murine AML models.

In vivo measurement of the Young's modulus of the cell wall of single root hairs

The paper measures the Young's modulus of single root hair cell walls using custom glass microplates as cantilevers to quantify mechanical properties.

Mechanical resistance of the environment affects root hair growth and nucleus dynamics

This study shows that mechanical resistance affects root hair growth speed and nucleus movement, with stiffer environments producing shorter root hairs and altered nucleus positioning.

Occurrence Of Avian Reovirus And Picobirnavirus In Wild Birds In An Environmental Protection Area In The Amazon Biome, Para, Brazil

This study detects avian reovirus and picobirnavirus in wild birds in Brazil's Amazon biome, reporting first occurrences in specific species and phylogenetic relationships to other isolates.

Variability in an effector gene promoter of a necrotrophic fungal pathogen dictates epistasis and effector-triggered susceptibility in wheat

This study identifies a promoter element in the Tox1 gene of Parastagonospora nodorum that regulates effector expression and susceptibility in wheat, revealing its role in pathogen virulence and host resistance.

Intracellular stiffening competes with cortical softening in glioblastoma cells

This study shows that glioblastoma cells are softer globally but stiffer intracellularly, suggesting mechanical phenotyping could be useful for diagnosis.

A distinct fingerprint of inflammatory mediators and miRNAs in Plasmodium vivax severe thrombocytopenia

The paper identifies inflammatory mediators and miRNAs associated with severe thrombocytopenia in Plasmodium vivax infections using proteomics, miRNA quantification, and machine learning.

Natural selection drives population divergence for local adaptation in a wheat pathogen

The paper uses QST-FST comparison and common garden experiments to show that natural selection drives local adaptation in wheat pathogen populations across different environmental conditions.

The impact of cell geometry and the cytoskeleton on the nucleo-cytoplasmic localisation of the SMYD3 methyltransferase suggests that the epigenetic machinery is mechanosensitive

This study shows that cell geometry affects SMYD3 methyltransferase localization, suggesting mechanosensitivity in epigenetic machinery.

Processing cookies formulated with goat cream enriched with conjugated linoleic acid

This study developed cookies using goat cream enriched with CLA and found that CGCLA cookies had higher CLA levels and comparable consumer acceptance to other formulations.

Precision phenotyping reveals novel loci for quantitative resistance to septoria tritici blotch in European winter wheat

The paper uses high-throughput automated phenotyping to identify novel genetic loci associated with quantitative resistance to septoria tritici blotch in wheat.