Author

D. Rai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

A. Akhmanova· 3 shared L. Blanchoin· 2 shared M. Thery· 2 shared A. A. Lee· 1 shared A. Aher· 1 shared A. Balesano· 1 shared A. Behzadi· 1 shared A. Ephron· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

A. Akhmanova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

M. R. Garnsey, M. C. Robinson, L. T. Nguyen, R. Cardin, J. Tillotson, E. Mashalidis, Y. Aijia, L. Aschenbrenner, A. Balesano, A. Behzadi, B. Boras, J. S. Chang, H. Eng, A. Ephron, T. Foley, , A. A. Lee

This study identifies potent SARS-CoV-2 PLpro inhibitors using machine learning, showing efficacy in a mouse model of COVID-19.

bioRxiv · Jan 26, 2024 · PreprintMicrobiology

CAMSAP-driven microtubule release from γ-TuRC and its regulation by nucleation-promoting factors

D. Rai, S. Hua, J. L. Monster, R. Stucchi, K. Stecker, Y. Zhang, E. A. Katrukha, M. A. Altelaar, M. Wieczorek, K. Jiang, A. Akhmanova

This study investigates how CAMSAP proteins and CDK5RAP2 regulate microtubule release from γ-TuRC, revealing their roles in microtubule nucleation and stabilization.

bioRxiv · Aug 3, 2022 · PreprintCell Biology

Compressive forces stabilise microtubules in living cells

Y. Li, O. Kucera, D. Cuvelier, D. M. Rutkowski, M. Deygas, D. Rai, T. Pavlovic, F. N. Vicente, M. Piel, G. Giannone, D. Vavylonis, A. Akhmanova, L. Blanchoin, M. Thery

The paper shows that compressive forces stabilize microtubules in living cells through CLASP2 relocation, indicating mechano-responsive properties.

bioRxiv · Feb 7, 2022 · PreprintCell Biology

CLASP mediates microtubule repair by promoting tubulin incorporation into damaged lattices

A. Aher, D. Rai, L. Schaedel, J. Gaillard, K. John, L. Blanchoin, M. Thery, A. Akhmanova

This study shows CLASP2 promotes microtubule lattice repair by facilitating tubulin incorporation into damaged sites and stabilizing partial protofilaments.

bioRxiv · Oct 17, 2019Cell Biology