Author

D. Sarrio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Rojo-Sebastian· 2 shared G. Moreno-Bueno· 2 shared L. Martinez· 2 shared A. Molina-Crespo· 1 shared A. TEIJO· 1 shared C. Bernado-Morales· 1 shared C. Gonzalo-Consuegra· 1 shared C. Ramos-Nebot· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Rojo-Sebastian

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2 papers

Recent·Most cited

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

M. Gamez-Chiachio, A. Molina-Crespo, C. Ramos-Nebot, J. Martinez-Val, L. Martinez, K. Gassner, F. J. Llobet, C. Gonzalo-Consuegra, M. Cordani, C. Bernado-Morales, E. Diaz, A. Rojo-Sebastian, J. C. Trivino, L. Sanchez, R. Rodriguez-Barrueco, , G. Moreno-Bueno

This study identifies GSDMB over-expression as a driver of HER2-targeted therapy resistance through autophagy induction and shows that combining lapatinib with chloroquine enhances therapeutic efficacy in GSDMB-positive tumors.

Journal of Experimental & Clinical Cancer Research · Sep 26, 2022Peer-reviewedCancer Biology

IN VIVO ANALYSIS OF THE ROLE OF GASDERMIN-B (GSDMB) IN CANCER USING NOVEL KNOCK-IN MOUSE MODELS

D. SARRIO, A. ROJO-SEBASTIAN, A. TEIJO, M. PEREZ-LOPEZ, E. DIAZ-MARTIN, L. MARTINEZ, S. MORALES, P. GARCIA-SANZ, J. PALACIOS, G. MORENO-BUENO

This study uses novel knock-in mouse models to investigate GSDMB2's role in cancer, finding it does not significantly drive tumorigenesis but may reduce gastric carcinogenesis.

bioRxiv · May 27, 2021Cancer Biology