Author

G. Moreno-Bueno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Rojo-Sebastian· 3 shared A. Teijo· 2 shared D. Sarrio· 2 shared L. Martinez· 2 shared A. Alonso de la Vega· 1 shared A. Jimenez-Segovia· 1 shared A. Molina-Crespo· 1 shared A. Monfort-Vengut· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

A. Rojo-Sebastian

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling.

C. Marugan, B. Ortigosa, N. Sanz-Gomez, A. Monfort-Vengut, C. Bertinetti, A. Teijo, M. Gonzalez, A. Alonso de la Vega, M. J. Lallena, G. Moreno-Bueno, G. de Carcer

The paper identifies TPX2 as a gene that increases breast cancer sensitivity to dasatinib by activating the YAP pathway, and shows TPX2 and YAP are biomarkers for poor prognosis and potential dasatinib therapy.

bioRxiv · Sep 4, 2023Cancer Biology

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

M. Gamez-Chiachio, A. Molina-Crespo, C. Ramos-Nebot, J. Martinez-Val, L. Martinez, K. Gassner, F. J. Llobet, C. Gonzalo-Consuegra, M. Cordani, C. Bernado-Morales, E. Diaz, A. Rojo-Sebastian, J. C. Trivino, L. Sanchez, R. Rodriguez-Barrueco, , G. Moreno-Bueno

This study identifies GSDMB over-expression as a driver of HER2-targeted therapy resistance through autophagy induction and shows that combining lapatinib with chloroquine enhances therapeutic efficacy in GSDMB-positive tumors.

Journal of Experimental & Clinical Cancer Research · Sep 26, 2022Peer-reviewedCancer Biology

IN VIVO ANALYSIS OF THE ROLE OF GASDERMIN-B (GSDMB) IN CANCER USING NOVEL KNOCK-IN MOUSE MODELS

D. SARRIO, A. ROJO-SEBASTIAN, A. TEIJO, M. PEREZ-LOPEZ, E. DIAZ-MARTIN, L. MARTINEZ, S. MORALES, P. GARCIA-SANZ, J. PALACIOS, G. MORENO-BUENO

This study uses novel knock-in mouse models to investigate GSDMB2's role in cancer, finding it does not significantly drive tumorigenesis but may reduce gastric carcinogenesis.

bioRxiv · May 27, 2021Cancer Biology

Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression.

A. Jimenez-Segovia, A. Mota, A. Rojo-Sebastian, B. Barrocal, A. Rynne-Vidal, M. L. Garcia-Bermejo, R. Gomez-Bris, L. J. A. C. Hawinkels, P. Sandoval, R. Garcia-Escudero, M. Lopez-Cabrera, G. Moreno-Bueno, M. Fresno, K. Stamatakis

This paper identifies PGF2α-induced TGFβ-PMEPA1 pathway as a driver of epithelial plasticity and ovarian cancer progression, with PMEPA1 as a therapeutic target and prognostic biomarker.

bioRxiv · Sep 18, 2018Cancer Biology

A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

M. I. Calvo Sanchez, E. Carrasco, S. Fernandez-Martos, G. Moreno-Bueno, C. Bernabeu, M. Quintanilla, J. Espada

This study identifies Endoglin as a key component in the molecular oscillator regulating hair follicle cycles by mediating feedback crosstalk between Wnt/β-catenin and Bmp/Smad signals.

bioRxiv · Dec 7, 2017Cell Biology