Author

A. Rojo-Sebastian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Moreno-Bueno· 3 shared D. Sarrio· 2 shared L. Martinez· 2 shared A. Jimenez-Segovia· 1 shared A. Molina-Crespo· 1 shared A. Mota· 1 shared A. Rynne-Vidal· 1 shared A. TEIJO· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

G. Moreno-Bueno

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

M. Gamez-Chiachio, A. Molina-Crespo, C. Ramos-Nebot, J. Martinez-Val, L. Martinez, K. Gassner, F. J. Llobet, C. Gonzalo-Consuegra, M. Cordani, C. Bernado-Morales, E. Diaz, A. Rojo-Sebastian, J. C. Trivino, L. Sanchez, R. Rodriguez-Barrueco, , G. Moreno-Bueno

This study identifies GSDMB over-expression as a driver of HER2-targeted therapy resistance through autophagy induction and shows that combining lapatinib with chloroquine enhances therapeutic efficacy in GSDMB-positive tumors.

Journal of Experimental & Clinical Cancer Research · Sep 26, 2022Peer-reviewedCancer Biology

IN VIVO ANALYSIS OF THE ROLE OF GASDERMIN-B (GSDMB) IN CANCER USING NOVEL KNOCK-IN MOUSE MODELS

D. SARRIO, A. ROJO-SEBASTIAN, A. TEIJO, M. PEREZ-LOPEZ, E. DIAZ-MARTIN, L. MARTINEZ, S. MORALES, P. GARCIA-SANZ, J. PALACIOS, G. MORENO-BUENO

This study uses novel knock-in mouse models to investigate GSDMB2's role in cancer, finding it does not significantly drive tumorigenesis but may reduce gastric carcinogenesis.

bioRxiv · May 27, 2021Cancer Biology

Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression.

A. Jimenez-Segovia, A. Mota, A. Rojo-Sebastian, B. Barrocal, A. Rynne-Vidal, M. L. Garcia-Bermejo, R. Gomez-Bris, L. J. A. C. Hawinkels, P. Sandoval, R. Garcia-Escudero, M. Lopez-Cabrera, G. Moreno-Bueno, M. Fresno, K. Stamatakis

This paper identifies PGF2α-induced TGFβ-PMEPA1 pathway as a driver of epithelial plasticity and ovarian cancer progression, with PMEPA1 as a therapeutic target and prognostic biomarker.

bioRxiv · Sep 18, 2018Cancer Biology