Author

D. Sui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 4 Organism:bacteria (other)· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

J. Hu· 5 shared Y. Jiang· 2 shared Y. Zhang· 2 shared C. Zhang· 1 shared E. Kuliyev· 1 shared G. Sharma· 1 shared G. Wei· 1 shared H. Takahashi· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersBiochemistry

J. Hu

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5 papers

Recent·Most cited

Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

Y. Jiang, Z. Li, D. Sui, G. Sharma, T. Wang, K. MacRenaris, H. Takahashi, K. Merz, J. Hu

This study rationally engineers ZIP8 to alter its substrate specificity, identifying a conditional selectivity filter that determines substrate preference based on transporter conformation.

bioRxiv · Jun 19, 2023Biochemistry

High-resolution structure of a mercury cross-linked ZIP metal transporter reveals delicate motions and metal relay for regulated zinc transport

T. Zhang, Y. Zhang, D. Sui, J. Hu

The paper reports a high-resolution crystal structure of a mercury-crosslinked ZIP transporter, revealing dynamic motions and a metal relay mechanism for zinc transport.

bioRxiv · Apr 20, 2023 · PreprintBiochemistry

Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor

S. Gatreddi, D. Sui, R. P. Hausinger, J. Hu

The paper shows sodium borohydride irreversibly inactivates lactate racemase by transferring hydride to the nickel-pincer nucleotide cofactor, revealing its reactivity.

bioRxiv · Nov 9, 2022Biochemistry

Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter

Y. Zhang, Y. Jiang, K. Gao, D. Sui, P. Yu, M. Su, G. Wei, J. Hu

This study determines the structural mechanism of a bacterial ZIP metal transporter, revealing an elevator-type transport mechanism through structural and computational analysis.

bioRxiv · Sep 14, 2022Biochemistry

Structural defects caused by Acrodermatitis Enteropathica mutations in the extracellular domain account for mistrafficking and malfunction of ZIP4

E. Kuliyev, C. Zhang, D. Sui, J. Hu

This study identifies structural defects in ZIP4's extracellular domain caused by AE mutations, leading to mistrafficking and loss of zinc uptake.

bioRxiv · Aug 16, 2020 · PreprintBiochemistry