D. Unnersjoe-Jess

Correlation of calcium multiphoton with ultrastructural STED imaging of the slit diaphragm in the same glomerulus.

The paper correlates calcium multiphoton imaging with STED imaging of the slit diaphragm in the same glomerulus to study kidney disease mechanisms.

Mechanical forces at the kidney filtration barrier govern spatial orientation of podocyte processes on capillaries

This study shows that podocyte processes align along the capillary axis to balance mechanical strain during kidney filtration.

PI 3-kinase isoform p110α mediated FOXO1 inactivation protects against aortic aneurysm formation

This study shows that p110α-mediated FOXO1 inactivation in smooth muscle cells prevents aortic aneurysm formation by maintaining vascular homeostasis and promoting reparative SMC phenotypes.

Three-dimensional Super-resolved Imaging of Paraffin-embedded Kidney Samples

This paper develops protocols for three-dimensional STED and confocal imaging of FFPE kidney tissue, achieving similar staining and image quality as previous methods.

Deep learning-based segmentation and quantification of podocyte foot process morphology

This paper develops a deep learning method to segment and quantify podocyte foot process morphology in kidney tissue, confirming morphological changes in disease states.