Author

J. Spitzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Schmidt· 2 shared A. Chinnaiyan· 1 shared A. Odainic· 1 shared A. Roers· 1 shared B. Mullan· 1 shared B. Steglich· 1 shared C. Hawkins· 1 shared C. Koschmann· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

S. Schmidt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PI 3-kinase isoform p110α mediated FOXO1 inactivation protects against aortic aneurysm formation

M. Vantler, M. Schorscher, E. M. Berghausen, M. Zierden, J. Spitzer, J. B. Moore, D. Wong, Z. Li, M. Wissmueller, L. Gnatzy-Feik, D. Unnersjoe-Jess, L.-M. A. Zimmermann, M. Grandoch, D. Mehrkens, M. Adam, , S. Rosenkranz

This study shows that p110α-mediated FOXO1 inactivation in smooth muscle cells prevents aortic aneurysm formation by maintaining vascular homeostasis and promoting reparative SMC phenotypes.

bioRxiv · Dec 1, 2022 · PreprintCell Biology

Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling

P. C. Hackstein, J. Spitzer, K. Symeonidis, H. Horvatic, T. Bedke, B. Steglich, L. Assmus, A. Odainic, N. Kessler, S. Klein, M. Beyer, R. Schmithausen, E. Latz, C. Kurts, J. Trebicka, , Z. Abdullah

The paper shows that liver injury suppresses systemic T cell immunity to viral infection, which can be reversed by inhibiting interferon and IL-10 signaling in preclinical models and human patients.

bioRxiv · Jul 21, 2022 · PreprintImmunology

Therapeutic reversal of prenatal pontine ID1 signaling in DIPG

V. N. Yadav, M. K. Harris, D. Messinger, C. Thomas, J. R. Cummings, T. Yang, R. Woo, R. Siddaway, M. Burkert, S. Stallard, T. Qin, B. Mullan, R. Siada, R. Ravindran, M. Niculcea, , C. Koschmann

This study identifies ID1 upregulation in DIPG tumor cells and shows that CBD can reduce ID1-driven invasiveness in vitro and in vivo.

bioRxiv · May 10, 2021 · PreprintCancer Biology