Author

L.-M. A. Zimmermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Sengle· 3 shared M. Grandoch· 3 shared D. Mehrkens· 2 shared S. Baldus· 2 shared A. Brueckner· 1 shared A. G. Furlan· 1 shared A. V. Zuk· 1 shared B. K. Fleischmann· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

G. Sengle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PI 3-kinase isoform p110α mediated FOXO1 inactivation protects against aortic aneurysm formation

M. Vantler, M. Schorscher, E. M. Berghausen, M. Zierden, J. Spitzer, J. B. Moore, D. Wong, Z. Li, M. Wissmueller, L. Gnatzy-Feik, D. Unnersjoe-Jess, L.-M. A. Zimmermann, M. Grandoch, D. Mehrkens, M. Adam, , S. Rosenkranz

This study shows that p110α-mediated FOXO1 inactivation in smooth muscle cells prevents aortic aneurysm formation by maintaining vascular homeostasis and promoting reparative SMC phenotypes.

bioRxiv · Dec 1, 2022 · PreprintCell Biology

Deficiency in hyaluronan synthase 3 attenuates ruptures in a murine model of abdominal aortic aneurysms by reduced aortic monocyte infiltration

T. Suvorava, F. Brack, J. Kaczur, P. Petzsch, K. Koehrer, C. Quast, N. Gerdes, K. Voigt, M. Krueger, J. Fischer, A. Brueckner, B. K. Fleischmann, D. Wenzel, L.-M. A. Zimmermann, G. Sengle, , M. Grandoch

This study shows that deficiency in HAS3 reduces aortic ruptures in a murine AAA model by decreasing monocyte infiltration and ECM degradation.

bioRxiv · Dec 1, 2022 · PreprintImmunology

Targeting of MMP-13 prevents aortic aneurysm formation in Marfan mice

L.-M. A. Zimmermann, A. G. Furlan, D. Mehrkens, S. Geissen, A. V. Zuk, G. Pryymachuk, N. Pykarek, T. van Beers, D. Sonntag-Bensch, J. Marzi, K. Schenke-Layland, J. Brinckmann, M. Grandoch, P. Zigrino, S. Baldus, G. Sengle

This study shows that targeting MMP-13 prevents aortic aneurysm formation in Marfan mice by reducing collagen degradation and BMP activity.

bioRxiv · Nov 30, 2022 · PreprintBiochemistry