Author

D. W. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

C. F. Basler· 2 shared G. K. Amarasinghe· 2 shared M. L. Gross· 2 shared R. A. Davey· 2 shared A. B. Moyle· 1 shared A. Hachim· 1 shared A. J. Qavi· 1 shared A. R. Cole· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. F. Basler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CAPG is required for Ebola virus infection by controlling virus egress from infected cells.

H. Mori, J. M. Connell, C. J. Donahue, R. Boytz, J. Patten, D. W. Leung, D. J. Lacount, R. A. Davey

This study identifies CAPG as a host factor required for Ebola virus infection by stabilizing actin filaments and facilitating viral egress from infected cells.

bioRxiv · Apr 10, 2022Microbiology

Effect of mutations in the SARS-CoV-2 spike protein on protein stability, cleavage, and cell-cell fusion function

C. T. Barrett, H. E. Neal, K. Edmonds, C. L. Moncman, R. Thompson, J. M. Branttie, K. B. Boggs, C.-Y. Wu, D. W. Leung, R. E. Dutch

This study examines how mutations in the SARS-CoV-2 spike protein affect its stability, cleavage, and ability to mediate cell-cell fusion.

bioRxiv · Jan 24, 2021 · PreprintMicrobiology

Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain

C. Wu, A. J. Qavi, A. Hachim, N. Kavian, A. R. Cole, A. B. Moyle, N. D. Wagner, J. Sweeney-Gibbons, H. W. Rohrs, M. L. Gross, J. S. M. Peiris, C. F. Basler, C. W. Farnsworth, S. A. Valkenburg, G. K. Amarasinghe, D. W. Leung

This study characterizes the SARS-CoV-2 N protein, identifying domain-specific functions and highlighting the C-terminal domain's immunogenicity for diagnostic applications.

bioRxiv · Nov 30, 2020Biochemistry

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

J. Batra, M. Anantpadma, G. I. Small, O. Shtanko, M. Zhang, D. Liu, C. G. Williams, N. Biedenkopf, S. Becker, M. L. Gross, D. W. Leung, R. A. Davey, G. K. Amarasinghe, N. J. Krogan, C. F. Basler

This study identifies non-canonical proline-tyrosine interactions in the Ebola virus VP30 protein that regulate viral replication by interacting with multiple host proteins.

bioRxiv · May 19, 2020Microbiology