Author

G. I. Small

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

A. Banerjee· 1 shared B. Chait· 1 shared C. F. Basler· 1 shared C. G. Williams· 1 shared D. Liu· 1 shared D. W. Leung· 1 shared E. A. Campbell· 1 shared G. K. Amarasinghe· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Banerjee

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2 papers

Recent·Most cited

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain

G. I. Small, O. Federova, P. D. B. Olinares, J. Chandanani, A. Banerjee, Y. J. Choi, H. Molina, B. Chait, S. A. Darst, E. A. Campbell

This study determines cryo-EM structures of SARS-CoV-2 NiRAN domain catalytic intermediates, revealing structural mechanisms for NMPylation and deRNAylation/capping, and explaining substrate preference for capping.

bioRxiv · Sep 25, 2023Biophysics

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

J. Batra, M. Anantpadma, G. I. Small, O. Shtanko, M. Zhang, D. Liu, C. G. Williams, N. Biedenkopf, S. Becker, M. L. Gross, D. W. Leung, R. A. Davey, G. K. Amarasinghe, N. J. Krogan, C. F. Basler

This study identifies non-canonical proline-tyrosine interactions in the Ebola virus VP30 protein that regulate viral replication by interacting with multiple host proteins.

bioRxiv · May 19, 2020Microbiology