Cooperative Effects of RIG-I-like Receptor Signaling and IRF1 on DNA Damage-Induced Cell Death
D. Y. Zander, S. S. Burkart, S. Wuest, V. G. Magalhaes, M. Binder
This study shows that RIG-I-like receptor signaling and IRF1 are both essential for DNA damage-induced cell death, with IRF1 regulated by ATM/ATR rather than RLRs.
bioRxiv · Oct 21, 2021Cell Biology