Author

S. S. Burkart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Binder· 4 shared D. Y. Zander· 2 shared J. Frankish· 2 shared S. Wuest· 2 shared A. Janda· 1 shared A. Pichlmair· 1 shared A. Piras· 1 shared A. Plociennikowska· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersImmunology

M. Binder

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Enhanced Airway Epithelial Response to SARS-CoV-2 Infection in Children is Critically Tuned by the Cross-Talk Between Immune and Epithelial Cells

V. Goncalves Magalhaes, S. Lukassen, M. Drechsler, J. Loske, S. S. Burkart, S. Wüst, E.-M. Jacobsen, J. Röhmel, M. A. Mall, K.-M. Debatin, R. Eils, S. Autenrieth, A. Janda, I. Lehmann, M. Binder

This study identifies enhanced cytokine-mediated cross-talk between immune and epithelial cells in children as a mechanism for their improved antiviral response to SARS-CoV-2.

bioRxiv · May 17, 2023Immunology

High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

S. S. Burkart, D. Schweinoch, J. Frankish, C. Sparn, S. Wuest, C. Urban, A. Piras, A. Pichlmair, J. Willemsen, L. Kaderali, M. Binder

This study characterizes the kinetics of RIG-I signaling and develops a dynamic model to predict antiviral responses and virus-host interactions.

bioRxiv · Aug 5, 2022Immunology

Cooperative Effects of RIG-I-like Receptor Signaling and IRF1 on DNA Damage-Induced Cell Death

D. Y. Zander, S. S. Burkart, S. Wuest, V. G. Magalhaes, M. Binder

This study shows that RIG-I-like receptor signaling and IRF1 are both essential for DNA damage-induced cell death, with IRF1 regulated by ATM/ATR rather than RLRs.

bioRxiv · Oct 21, 2021Cell Biology

A hetero-oligomeric remorin-receptor complex regulates plant development

N. B. Abel, C. A. Buschle, C. Hernandez-Ryes, S. S. Burkart, A.-F. Deroubaix, J. Mergner, J. Gronnier, I. K. Jarsch, J. Folgmann, K. H. Braun, E. Bayer, V. Germain, P. Derbyshire, F. L. H. Menke, B. Kemmerling, , T. Ott

The paper shows that Group 1 remorins form a hetero-oligomeric complex at the plasma membrane, recruiting RIR1 and NILR2 to regulate plant development.

bioRxiv · Jan 28, 2021 · PreprintPlant Biology

SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

C. J. Neufeldt, B. Cerikan, M. Cortese, J. Frankish, J.-Y. Lee, A. Plociennikowska, F. Heigwer, S. Joecks, S. S. Burkart, D. Y. Zander, M. Gendarme, B. El Debs, N. Halama, U. Merle, M. Boutros, , R. Bartenschlager

This study shows SARS-CoV-2 triggers a pro-inflammatory cytokine response via cGAS-STING and NF-κB in epithelial cells, which may contribute to severe disease.

bioRxiv · Jul 21, 2020Microbiology