Author

D.A.M. Heijnen

Cancer Center Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander FishiD· 1 shared Alsya J. AffandiiD· 1 shared Angeliki MoutsiopoulouiD· 1 shared Astrid P. HeikemaiD· 1 shared E.A. Große Wichtrup· 1 shared Enrico MastrobattistaiD· 1 shared Gillian DekkersiD· 1 shared Hendrik J. BrinkiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander FishORCID

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1 paper

Recent·Most cited

Identification of allo- or orthosteric VHH/single-domain antibodies that enhance or block pathogen binding to Siglec-1 on dendritic cells

Hendrik J. Brink, Alsya J. Affandi, Sandra Man-Bovenkerk, N.C.C.T. Dekker, E.A. Große Wichtrup, Rianne G. Bouma, Negisa Seyed Toutounchi, Veronique A. L. Konijn, Joeke G. C. Stolwijk, John L. van Hamme, Katarzyna Olesek, D.A.M. Heijnen, Alexander Fish, Angeliki Moutsiopoulou, Patrick H. N. Celie, , Joke M. M. den Haan

The paper identifies VHH/single-domain antibodies that either block or enhance Siglec-1 ligand binding to sialylated pathogens on dendritic cells.

bioRxiv · Dec 22, 2025 · PreprintImmunology