Author

Katarzyna Olesek

Cancer Center AmsterdamORCID 0000-0002-8929-1355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Yvette van KooykiD· 2 shared Alexander FishiD· 1 shared Alsya J. AffandiiD· 1 shared Angeliki MoutsiopoulouiD· 1 shared Astrid P. HeikemaiD· 1 shared Babet O. Springer· 1 shared Christian BlankiD· 1 shared D.A.M. Heijnen· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Yvette van KooykORCID

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2 papers

Recent·Most cited

CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanoma

Magalí B. Coccimiglio, Sofia Ibáñez‐Molero, Babet O. Springer, Laura J. W. Kruijssen, Georgia Clayton, Reece Davison, Tao Zhang, S C M A Wijnen, Ernesto Rodríguez, Katarzyna Olesek, S. Veenstra, Thomas van den Brekel, Eleonora Nardini, Joelle van Elk, Eelco D. Keuning, , Yvette van Kooyk

The paper shows CMAS in melanoma cells correlates with poor survival and reduced response to immunotherapy by altering tumor-immune interactions.

bioRxiv · Apr 29, 2026 · PreprintCancer Biology

Identification of allo- or orthosteric VHH/single-domain antibodies that enhance or block pathogen binding to Siglec-1 on dendritic cells

Hendrik J. Brink, Alsya J. Affandi, Sandra Man-Bovenkerk, N.C.C.T. Dekker, E.A. Große Wichtrup, Rianne G. Bouma, Negisa Seyed Toutounchi, Veronique A. L. Konijn, Joeke G. C. Stolwijk, John L. van Hamme, Katarzyna Olesek, D.A.M. Heijnen, Alexander Fish, Angeliki Moutsiopoulou, Patrick H. N. Celie, , Joke M. M. den Haan

The paper identifies VHH/single-domain antibodies that either block or enhance Siglec-1 ligand binding to sialylated pathogens on dendritic cells.

bioRxiv · Dec 22, 2025 · PreprintImmunology