Author

John L. van Hamme

Amsterdam University Medical CentersORCID 0000-0003-0765-9441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander FishiD· 1 shared Alsya J. AffandiiD· 1 shared Angeliki MoutsiopoulouiD· 1 shared Astrid P. HeikemaiD· 1 shared D.A.M. Heijnen· 1 shared E.A. Große Wichtrup· 1 shared Enrico MastrobattistaiD· 1 shared Gillian DekkersiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander FishORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Identification of allo- or orthosteric VHH/single-domain antibodies that enhance or block pathogen binding to Siglec-1 on dendritic cells

Hendrik J. Brink, Alsya J. Affandi, Sandra Man-Bovenkerk, N.C.C.T. Dekker, E.A. Große Wichtrup, Rianne G. Bouma, Negisa Seyed Toutounchi, Veronique A. L. Konijn, Joeke G. C. Stolwijk, John L. van Hamme, Katarzyna Olesek, D.A.M. Heijnen, Alexander Fish, Angeliki Moutsiopoulou, Patrick H. N. Celie, , Joke M. M. den Haan

The paper identifies VHH/single-domain antibodies that either block or enhance Siglec-1 ligand binding to sialylated pathogens on dendritic cells.

bioRxiv · Dec 22, 2025 · PreprintImmunology