The critical role of enterovirus 2A protease in viral translation, replication, and antagonism of host antiviral responses.
Jelle G. Schipper, Chiara Aloise, Sereina O. Sutter, Marleen Zwaagstra, Arno L. W. van Vliet, Rana Abdelnabi, Bob J. Ignacio, Kimberly M. Bonger, Dagmar Roelofs, Judith M. A. van den Brand, Richard Wubbolts, Lucas J. M. Bruurs, Hendrik Jan Thibaut, Johan H. Neyts, Marvin E. Tanenbaum, Frank J. M. van Kuppeveld
This study demonstrates that enterovirus 2A protease is critical for viral replication and evasion of host antiviral responses through multiple mechanisms.
bioRxiv · Feb 20, 2025 · PreprintMicrobiology