Identification of picornavirus proteins that inhibit de novo nucleotide synthesis during infection
Lonneke V. Nouwen, Esther A. Zaal, Inge Buitendijk, Marleen Zwaagstra, Chiara Aloise, Arno L. W. van Vliet, Jelle G. Schipper, Alain van Mil, Celia R. Berkers, Frank J. M. van Kuppeveld
This study identifies picornavirus proteins that inhibit de novo nucleotide synthesis during infection using metabolomics and recombinant virus analysis.
PLoS Pathogens · Jul 3, 2025Peer-reviewedMicrobiology