Author

Chiara Aloise

Utrecht University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Frank J. M. van KuppeveldiD· 3 shared Arno L. W. van Vliet· 2 shared Jelle G. Schipper· 2 shared Marleen ZwaagstraiD· 2 shared Alain van MiliD· 1 shared Belén Lizcano-PerretiD· 1 shared Bob J. IgnacioiD· 1 shared Catherine Sadzot· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Frank J. M. van KuppeveldORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cardiovirus-Mediated PKR Inhibition Results from Nucleocytoplasmic Trafficking Disruption

Romane Milcamps, Belén Lizcano-Perret, Fanny Wavreil, Marielle Lebrun, Chiara Aloise, Didier Vertommen, Gaëtan Herinckx, Frank J. M. van Kuppeveld, Catherine Sadzot, Thomas Michiels

This study shows that cardiovirus L protein disrupts nucleocytoplasmic trafficking, leading to PKR inhibition by sequestering PKR in nucleoli and releasing nuclear RNA-binding proteins into the cytosol.

PLoS Pathogens · Dec 17, 2025Peer-reviewedImmunology

Identification of picornavirus proteins that inhibit de novo nucleotide synthesis during infection

Lonneke V. Nouwen, Esther A. Zaal, Inge Buitendijk, Marleen Zwaagstra, Chiara Aloise, Arno L. W. van Vliet, Jelle G. Schipper, Alain van Mil, Celia R. Berkers, Frank J. M. van Kuppeveld

This study identifies picornavirus proteins that inhibit de novo nucleotide synthesis during infection using metabolomics and recombinant virus analysis.

PLoS Pathogens · Jul 3, 2025Peer-reviewedMicrobiology

The critical role of enterovirus 2A protease in viral translation, replication, and antagonism of host antiviral responses.

Jelle G. Schipper, Chiara Aloise, Sereina O. Sutter, Marleen Zwaagstra, Arno L. W. van Vliet, Rana Abdelnabi, Bob J. Ignacio, Kimberly M. Bonger, Dagmar Roelofs, Judith M. A. van den Brand, Richard Wubbolts, Lucas J. M. Bruurs, Hendrik Jan Thibaut, Johan H. Neyts, Marvin E. Tanenbaum, Frank J. M. van Kuppeveld

This study demonstrates that enterovirus 2A protease is critical for viral replication and evasion of host antiviral responses through multiple mechanisms.

bioRxiv · Feb 20, 2025 · PreprintMicrobiology