Author

Daosheng Ai

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Wenzhi SuniD· 4 shared Jun-Liszt LiiD· 3 shared Woo‐Ping GeiD· 3 shared Xing-jun CheniD· 3 shared Ziyan Feng· 3 shared Fengzhi LiiD· 2 shared Xiaoxiao ZouiD· 2 shared Zhanying BiiD· 2 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersNeuroscience

Wenzhi SunORCID

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Author profile →

5 papers

Recent·Most cited

rAAV-miniBEND: A targeted vector for brain endothelial cell gene delivery and cerebrovascular malformation modeling

Jun-Liszt Li, Zhanying Bi, Xing-jun Chen, Tianyue Ming, Baoshan Qiu, Fengzhi Li, Ziyan Feng, Daosheng Ai, Tingting Zhang, Jiayu Wang, Shuai Lin, Yiping Lu, Zhen Wang, Juan Huang, Fei Zhao, , Woo‐Ping Ge

The paper develops a rAAV vector, rAAV-miniBEND, for specific gene delivery to brain endothelial cells and models cerebrovascular malformations like CCM and AVM.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

Inferring metabolite states from spatial transcriptomes using multiple graph neural network

Jiaxu Luo, Daosheng Ai, Wenzhi Sun

This paper introduces MGFEA, a method to infer metabolite states from spatial transcriptomes and improve accuracy using multi-omics data.

bioRxiv · Jun 12, 2024 · PreprintBioinformatics

The subcommissural organ regulates brain development via secreted peptides

Tingting Zhang, Daosheng Ai, Pingli Wei, Ying Xu, Zhanying Bi, Fengfei Ma, Fengzhi Li, Xing-jun Chen, Zhaohuan Zhang, Xiaoxiao Zou, Zongpei Guo, Yue Zhao, Jun-Liszt Li, Meng Ye, Ziyan Feng, , Woo‐Ping Ge

The paper identifies three genes highly expressed in the subcommissural organ (SCO) and shows their ablation causes brain developmental defects, with peptide reintroduction rescuing these defects.

Nature Neuroscience · May 13, 2024Peer-reviewedNeuroscience

ADAM10 mediates macroglial cell fate decisions in the developing brain

Yihui Wang, Yue Liang, Daosheng Ai, Jun-Liszt Li, Ziyan Feng, Zhibao Guo, Xing-jun Chen, Tingting Zhang, Xiaoxiao Zou, Junli Gao, Xiaofei Gao, Xiao-Ling Hu, Long‐Jun Wu, Wenzhi Sun, Suiqiang Zhu, , Woo‐Ping Ge

The paper shows ADAM10 regulates macroglial cell fate by promoting astrocyte generation and inhibiting oligodendrocyte production in developing brains.

bioRxiv · Feb 11, 2023 · PreprintNeuroscience

Accurate loop calling for 3D genomic data with cLoops

Yaqiang Cao, Zhaoxiong Chen, Xingwei Chen, Daosheng Ai, Guoyu Chen, Joseph McDermott, Yi Huang, Xiaoxiao Guo, Jing‐Dong J. Han

cLoops improves 3D genomic loop detection by analyzing paired-end tags directly, showing less distance bias and higher enrichment than existing tools.

Bioinformatics · Aug 20, 2019Peer-reviewedBioinformatics