Gene regulatory networks controlling temporal patterning, neurogenesis and cell fate specification in the mammalian retina.
Pin Lyu, Thanh V. Hoang, Clayton P. Santiago, Eric D. Thomas, Andrew E. Timms, Haley Appel, Megan Y. Gimmen, Nguyet Le, Lizhi Jiang, Dong Won Kim, Siqi Chen, David F. Espinoza, Ariel E. Telger, Kurt Weir, Brian S. Clark, , Seth Blackshaw
This study identifies gene regulatory networks controlling retinal development by integrating single-cell RNA and ATAC-seq data from mouse and human retinas, revealing transcription factors that regulate temporal patterning and cell fate.
Cell Reports · Nov 1, 2021Peer-reviewedNeuroscience