Lizhi Jiang

This study shows that overexpressing Meis1 and Meis2 in postnatal mouse retinal progenitor cells has distinct effects on temporal identity and neurogenesis, without fully reprogramming cell fate.

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

This study identifies gene regulatory networks controlling retinal development by integrating single-cell RNA and ATAC-seq data from mouse and human retinas, revealing transcription factors that regulate temporal patterning and cell fate.

This study identifies NFI factors as repressors of tanycyte-derived neurogenesis and shows their disruption promotes proliferation and neurogenesis in the hypothalamus.

This study identifies gene regulatory networks controlling proliferative and neurogenic competence in retinal Muller glia.