Author

David Gacquer

Université Libre de Bruxelles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Vincent DetoursiD· 2 shared Adam Shlien· 1 shared Adèle Herpoel· 1 shared Angéline Bilheu· 1 shared Anne Lefort· 1 shared Christine Desmedt· 1 shared Christos Sotiriou· 1 shared David Brown· 1 shared

Activity by Year

2015-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Vincent DetoursORCID

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2 papers

Recent·Most cited

Hominin-specific NOTCH2 paralogs expand human cortical neurogenesis through regulation of Delta/Notch interactions.

Ikuo Suzuki, David Gacquer, Roxane Van Heurck, Devesh Kumar, Marta Wojno, Angéline Bilheu, Adèle Herpoel, Nelle Lambert, Julian Chéron, Franck Polleux, Vincent Detours, Pierre Vanderhaeghen

The paper identifies hominin-specific NOTCH2 paralogs that enhance human cortical neurogenesis by modulating Delta/Notch interactions.

Cell · May 1, 2018Peer-reviewedDevelopmental Biology

Principles governing A-to-I RNA editing in the breast cancer transcriptome

Debora Fumagalli, David Gacquer, Françoise Rothé, Anne Lefort, Frederick Libert, David Brown, Naima Kheddoumi, Adam Shlien, Tomasz Konopka, Roberto Salgado, Denis Larsimont, Kornelia Polyak, Karen Willard-Gallo, Christine Desmedt, Martine Piccart, , Vincent Detours

This study identifies ADAR expression and inflammation as key regulators of A-to-I RNA editing in breast cancer, showing increased editing frequency in tumors and its impact on cell proliferation and apoptosis.

Cell Reports · Oct 1, 2015Peer-reviewedGenomics