Author
Université Libre de Bruxelles
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Anja van Benthem, Ridha Limame, Matteo Piumatti…·Pierre Vanderhaeghen
This study shows ASPM mutations disrupt mitotic spindle orientation in human cortical progenitors, leading to premature oRGC generation and reduced cortical progenitor numbers.
Baptiste Libé‐Philippot, Amélie Lejeune, Keimpe D. B. Wierda…·Pierre Vanderhaeghen
This study identifies LRRC37B as a human-specific gene that modulates neuronal excitability by interacting with voltage-gated sodium channels in cortical pyramidal neurons.
Roxane Van Heurck, Marta Wojno, Ikuo Suzuki…·Pierre Vanderhaeghen
This study identifies CROCCP2 as a human-specific gene that enhances cortical progenitor expansion by modulating cilia dynamics and mTOR signalling.
Daniele Linaro, Ben Vermaercke, Ryohei Iwata…·Pierre Vanderhaeghen
This study transplants human cortical neurons into mice to study their development and integration into mouse visual circuits, finding prolonged juvenile features and functional synaptic integration.
Jérôme Bonnefont, Luca Tiberi, Jelle van den Ameele…·Pierre Vanderhaeghen
The paper shows Bcl6 promotes neurogenic conversion by repressing extrinsic self-renewal pathways like Wnt through transcriptional silencing.
Ikuo Suzuki, David Gacquer, Roxane Van Heurck…·Pierre Vanderhaeghen
The paper identifies hominin-specific NOTCH2 paralogs that enhance human cortical neurogenesis by modulating Delta/Notch interactions.