Author

Adèle Herpoel

Université Libre de Bruxelles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Angéline Bilheu· 4 shared Pierre VanderhaegheniD· 4 shared Catherine A. LedentiD· 2 shared Emir ErkoliD· 2 shared Fausto D. Velez-BravoiD· 2 shared Ikuo SuzukiiD· 2 shared Jérôme BonnefontiD· 2 shared Marta WojnoiD· 2 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersNeuroscience

Angéline Bilheu

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 25, 2023

The microcephaly gene ASPM is required for the timely generation of human outer-radial glia progenitors by controlling mitotic spindle orientation

Anja van Benthem, Ridha Limame, Matteo Piumatti…·Pierre Vanderhaeghen

This study shows ASPM mutations disrupt mitotic spindle orientation in human cortical progenitors, leading to premature oRGC generation and reduced cortical progenitor numbers.

2 citations

humanexperimental assay

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NeurosciencebioRxivPreprintJun 17, 2020

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signalling to promote expansion of cortical progenitors.

Roxane Van Heurck, Marta Wojno, Ikuo Suzuki…·Pierre Vanderhaeghen

This study identifies CROCCP2 as a human-specific gene that enhances cortical progenitor expansion by modulating cilia dynamics and mTOR signalling.

2 citations

humanmouse

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NeuroscienceNeuronPeer-reviewedJul 25, 2019

Bcl6 promotes neurogenic conversion through transcriptional repression of multiple self-renewal-promoting extrinsic pathways.

Jérôme Bonnefont, Luca Tiberi, Jelle van den Ameele…·Pierre Vanderhaeghen

The paper shows Bcl6 promotes neurogenic conversion by repressing extrinsic self-renewal pathways like Wnt through transcriptional silencing.

65 citations

mousebulk RNA-seq

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Developmental BiologyCellPeer-reviewedMay 1, 2018

Hominin-specific NOTCH2 paralogs expand human cortical neurogenesis through regulation of Delta/Notch interactions.

Ikuo Suzuki, David Gacquer, Roxane Van Heurck…·Pierre Vanderhaeghen

The paper identifies hominin-specific NOTCH2 paralogs that enhance human cortical neurogenesis by modulating Delta/Notch interactions.

471 citationstop 1%

humanbulk RNA-seq

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