Anne Lefort

Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish

This study shows that cholangiocytes generate new hepatocytes during zebrafish liver regeneration after partial injury during growth.

Synaptic Gpr85 influences cerebellar granule cells electrical properties and light-induced behavior.

This study identifies Gpr85 as a synaptically enriched modulator of neuronal excitability and light-induced behavior in zebrafish.

An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration

The paper identifies an Lgr5-independent developmental lineage in mouse intestinal regeneration through single-cell RNA sequencing and lineage tracing experiments.

Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis

This study examines duodenal organoids from MASH patients and finds altered digestive homeostasis and junctional protein misexpression without barrier dysfunction.

Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland

The paper uses single-cell transcriptomics to reveal heterogeneity in zebrafish thyroid thyrocytes and characterizes surrounding cell types.

Lgr5 Controls Extracellular Matrix Production By Stem Cells In The Developing Intestine

This study shows Lgr5 regulates extracellular matrix production in fetal intestinal stem cells, affecting their maturation and niche environment.

Principles governing A-to-I RNA editing in the breast cancer transcriptome

This study identifies ADAR expression and inflammation as key regulators of A-to-I RNA editing in breast cancer, showing increased editing frequency in tumors and its impact on cell proliferation and apoptosis.