A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity
Eban A. Hanna, Ashleigh J. Crawford, Wenxuan Du, Adrian C. Johnston, David Schell, Zeqi Wan, Ting-Hsi Chen, Fan Wu, Kehan Ren, Yeongseo Lim, Vasco Queiroga, Praful R. Nair, Denis Wirtz
This paper introduces a 3D in vitro assay to study immune cell infiltration and cytotoxicity in solid tumors, showing it captures key steps of immune cell interaction with the tumor microenvironment.
Cell Reports Methods · Feb 1, 2026Peer-reviewedCancer Biology